TELIK ANNOUNCES CONFERENCE CALL AND WEBCAST TO DISCUSS SECOND QUARTER 2003 FINANCIAL RESULTS AND PROVIDE COMPANY UPDATE

Palo Alto, CA, July 25, 2003 — Telik, Inc. (Nasdaq: TELK) announced that its second quarter 2003 conference call and webcast will be held on Wednesday, July 30, 2003 at 4:30 p.m. Eastern time (1:30 p.m. Pacific time). The call will follow the release of Telik’s second quarter 2003 financial results earlier that day. Michael M. Wick M.D., Ph.D., Telik’s chairman and chief executive officer, and Cynthia M. Butitta, the company’s chief operating officer and chief financial officer, will present the company’s financial results and discuss progress in Telik’s clinical development programs.

Participants may access the live webcast via Telik’s website at www.telik.com or by telephone at (612) 288 0318. A replay of the webcast will be available on the Telik website from approximately 8:30 p.m. Eastern time on July 30 through August 6, 2003.

Telik, Inc. of Palo Alto, CA is a biopharmaceutical company working to discover, develop and commercialize small molecule drugs to treat serious diseases for which there is significant demand for new therapies. The company’s most advanced drug development candidate is TELCYTA™ (TLK286), a tumor activated small molecule drug that is in a Phase 3 registration clinical trial in ovarian cancer and in clinical trials in non-small cell lung, colorectal and breast cancer. TLK199 is in a Phase 1-2a trial in myelodysplastic syndrome, a form of pre-leukemia. Telik’s product candidates were discovered using its proprietary drug discovery technology, TRAP, which enables the rapid and efficient discovery of small molecule drug candidates. Additional information is available at www.telik.com.

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Contact:
Carol DeGuzman
Senior Director, Corporate Communications
Telik, Inc.
Tel 650-845-7728
Email cdeguzman@telik.com


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