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Palo Alto, CA, May 28, 2003 — Telik, Inc. (Nasdaq:
TELK) announced the following presentations on its TELCYTA™
(TLK286) product candidate at the American Society of Clinical Oncology
(ASCO) meeting in Chicago:
Phase 2 Study of TLK286 Administered Weekly in Patients with Non-Small
Cell Lung Cancer Who Failed Prior Platinum-Based Regimens (abstract
#2636); Saturday, May 31, 9:00 a.m. — 1:00 p.m.
Phase 2 Study of TLK286 Administered Weekly in Patients with Platinum
Refractory or Resistant Third-Line or Greater Advanced Ovarian Cancer
(abstract #1816); Sunday, June 1, 1:00 — 5:00 p.m.
Phase 2 Study of TELK286 as Third-Line or Greater Therapy in Patients
with Advanced Metastatic Breast Cancer (abstract # 61); Monday,
June 2, 8:00 a.m. — noon
TELCYTA™ is a small molecule prodrug which is activated by
GST P1-1, an enzyme present in higher levels in many human cancers
than in normal tissues. Upon activation, an intracellular process
known as apoptosis, or programmed cell death, is initiated. TELCYTA™,
which has been evaluated in clinical trials in more than 370 patients,
was discovered through the application of Telik’s proprietary
drug discovery technology, TRAP. Telik has retained worldwide commercialization
rights.
About Telik, Inc.
Telik, Inc. of Palo Alto, CA is a biopharmaceutical company working
to discover, develop and commercialize small molecule drugs to treat
serious diseases for which there is significant demand for new therapies.
The company’s most advanced drug development candidate is
TELCYTA™, in a Phase 3 registration trial in advanced ovarian
cancer, and in earlier stage clinical trials in ovarian, non-small
cell lung and breast cancer. Telik’s product candidates were
discovered using its proprietary technology, TRAP, which enables
the rapid and efficient discovery of small molecule drug candidates.
Additional information is available at www.telik.com.
You should not rely on forward-looking statements contained in
this press release, including statements regarding our ability to
successfully develop TELCYTA™ for the treatment of any cancer,
its tolerability, potential efficacy or market potential. Telik
can give no assurance with regard to these statements. None of our
products have been determined to be safe or effective in humans
or been approved for marketing. Substantial additional testing,
including randomized, controlled clinical trials of TELCYTA™
will be necessary prior to seeking marketing approval. There can
be no assurance that such trials will accrue sufficient patients,
be conducted with sufficient quality, in a timely manner, have a
successful outcome, or that regulatory approval will be obtained.
In addition, we are reliant on external manufacturing, and any interruption
or delay in drug supply could adversely affect the development program.
More detailed information regarding factors that may cause actual
results to differ materially from the results expressed or implied
by statements in this press release may be found in Telik’s
periodic filings with the Securities and Exchange Commission. Telik
assumes no obligation to update any information in this press release.
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Contact:
Carol DeGuzman
Senior Director, Corporate Communications
Telik, Inc.
Tel 650-845-7728
Email cdeguzman@telik.com
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