TELIK ANNOUNCES QUARTERLY FINANCIAL RELEASE, CONFERENCE CALL AND WEBCAST

Palo Alto, CA, April 18, 2003 — Telik, Inc. (Nasdaq: TELK) announced that its quarterly conference call and webcast has been scheduled for Thursday, April 24, 2003 at 4:30 p.m. Eastern time. The call will follow the release of Telik’s first quarter 2003 financial results on April 24, 2003.

Participants may access the live webcast via Telik’s website at www.telik.com or by telephone at (612) 332-0107. A replay of the webcast will be available on the Telik website from approximately 8:30 p.m. Eastern time on April 24 through May 1, 2003.

Telik, Inc. of Palo Alto, CA is a biopharmaceutical company working to discover, develop and commercialize small molecule drugs to treat serious diseases for which there is significant demand for new therapies. The company’s most advanced drug development candidate is TLK286, a tumor activated small molecule drug that is in a Phase 3 registration clinical trial in ovarian cancer and in clinical trials in non-small cell lung, colorectal and breast cancer. TLK199 is in a Phase 1-2a trial in myelodysplastic syndrome, a form of pre-leukemia. Telik’s product candidates were discovered using its proprietary drug discovery technology, TRAP, which enables the rapid and efficient discovery of small molecule drug candidates. Additional information is available at www.telik.com.

You should not rely on forward-looking statements contained in this press release, including statements regarding the potential for TLK286 or TLK199 to treat one or more types of cancer. Telik can give no assurance with regard to these statements. The application of TRAP to additional new drug discovery may not yield additional product candidates. TLK286 and TLK199 are in clinical development and have not been approved for marketing, and there can be no assurance that the clinical trials required to successfully develop these compounds will have a successful outcome, or that regulatory approval will be obtained. Telik is reliant on external manufacturing of TLK286 and TLK199. More detailed information regarding factors that may cause actual results to differ materially from the results expressed or implied by statements in this press release may be found in Telik’s periodic filings with the Securities and Exchange Commission. Telik assumes no obligation to update any information in this press release.

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Contact:
Carol DeGuzman
Senior Director, Corporate Communications
Telik, Inc.
Tel 650-845-7728
Email cdeguzman@telik.com


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