TELIK ANNOUNCES ADDITIONS TO BOARD OF DIRECTORS

Palo Alto, CA, April 2, 2003 — Telik, Inc. (Nasdaq: TELK) announced the election of Robert W. Frick and Richard B. Newman to the company’s Board of Directors.

Mr. Frick was formerly a senior executive with Bank of America, serving in various capacities including Vice Chairman of the Board, Chief Financial Officer, head of the World Banking Group, Managing Director of BankAmerica International, and President of Bank of America’s venture capital subsidiary. He is currently a consultant on business strategy, organizational structure and financial issues for a number of client companies, and serves on the boards of directors of several private companies. He is an Adjunct Professor of Business Strategy in the graduate business program at St. Mary’s College.

Richard Newman is President and Chief Executive Officer of D&R Products Co., Inc., which designs, develops and manufactures orthopedic, vascular and other surgical medical devices and instruments for major medical device and instrument manufacturers in the United States and Europe. An attorney, he has more than 30 years’ experience in acquiring and operating industrial, real estate and software businesses.

"Bob Frick and Richard Newman each bring a wealth of executive, business and financial experience to Telik," said Chairman and Chief Executive Officer Michael M. Wick, M.D., Ph.D. "We look forward to the contributions they will make as we advance the development of more effective drugs to treat cancer patients and grow Telik into a commercial company ."

Telik, Inc. of Palo Alto, CA is a biopharmaceutical company working to discover, develop and commercialize small molecule drugs to treat serious diseases for which there is significant demand for new therapies. The company’s most advanced drug development candidates are TLK286, a tumor activated small molecule drug that is in Phase 2 clinical trials in ovarian, non-small cell lung, colorectal and breast cancer, and TLK199, a small molecule myelostimulant. Telik’s product candidates were discovered using its proprietary drug discovery technology, TRAP, which enables the rapid and efficient discovery of small molecule drug candidates. Additional information is available at www.telik.com.

You should not rely on forward-looking statements contained in this press release, including statements regarding the potential for TLK286 or TLK199 to treat one or more types of cancer. Telik can give no assurance with regard to these statements. TLK286 and TLK199 are in clinical development and have not been approved for marketing, and there can be no assurance that the clinical trials required to successfully develop these compounds will have a successful outcome, or that regulatory approval will be obtained. Telik is reliant on external manufacturing of TLK286 and TLK199. More detailed information regarding factors that may cause actual results to differ materially from the results expressed or implied by statements in this press release may be found in Telik’s periodic filings with the Securities and Exchange Commission. Telik assumes no obligation to update any information in this press release.

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Contact:
Carol DeGuzman
Senior Director, Corporate Communications
Telik, Inc.
Tel 650-845-7728
Email cdeguzman@telik.com


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