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Telik is conducting clinical trials of two drug candidates:
TELINTRA® (Ezatiostat HCl, TLK199) and
TELCYTA® (Canfosfamide HCl, TLK286).
Click on the links below for additional information.
TELINTRA®
TELCYTA®
 Ovarian
Cancer
Non-Small
Cell Lung Cancer
What is a Clinical Trial?
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Indication |
Clinical Trial |
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Phase 1 |
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Phase 2 |
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Phase 3 |
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Ovarian Cancer |
ASSIST-1 |
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ASSIST-3 (Carboplatin + TELCYTA) |
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ASSIST-5 (Doxil® + TELCYTA) |
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Non-Small Cell
Lung Cancer |
ASSIST-2 |
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| Carboplatin + Taxol® + TELCYTA |
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Cisplatin + TELCYTA (1st Line) |
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Colorectal Cancer |
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Breast Cancer |
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A clinical trial is a research study that is designed to evaluate
a new drug or combination of drugs. Clinical studies are conducted
in human volunteers and are the basis of our knowledge of new treatments
and whether or not they are safe and effective enough for the general
public. If the information gathered in clinical trials of a certain
drug suggests that the drug may provide a benefit and is safe, the
results are submitted to the Food and Drug Administration (FDA)
for review. The FDA decides whether or not the drug will be approved
for public use.
Participation in a clinical trial may help to answer important
scientific questions that ultimately may benefit the care of patients
in the future. Becoming involved in a clinical trial may provide
exposure to a new drug or therapy that may provide benefit. However,
there is no guarantee that an experimental drug will work. In addition,
most clinical trials have what is known as a control group that
serves as the basis for comparison of the new treatment. Participants
are randomly selected to receive either the experimental treatment
or the control, which in the case of cancer, is often a drug or
treatment that is already approved for the condition.
In addition to how well a therapy works, clinical trials also investigate
side effects that may be caused by a new drug. Because the treatment
is experimental, side effects are often not predictable or known.
Below is a list of basic pros and cons, but it is by no means a
complete list. To learn more about the pros and cons of clinical
trials, talk to your doctor.
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Pro: A new therapy may provide benefit
over available treatments
Con: The new therapy may not work well |
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Pro: The side effects of the new therapy
may be mild compared to available treatments
Con: The side effects of the new therapy may be more
severe than the other available treatments |
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Pro: The participant will get the same
quality of care from the physicians and research staff during
the course of the study, regardless of which therapy the participant
receives
Con: The participant is not able to choose which therapy
she will receive |
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Pro: Participants are followed closely
by the research team
Con: Participants may be required to visit their doctor
more often and more testing may be needed |
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There are many web sites that provide detailed information about
clinical trial participation. In particular, the National Institute
of Health (NIH) Web site, clinicaltrials.gov,
provides a wealth of valuable information. To go directly to the
NIH Frequently Asked Questions about Clinical Trials page, click
here.
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